Odontogenic myxoma a rare case and diagnostic and therapeutic challenges elitsa g. Differential diagnosis in adults and children includes a wide variety of other benign but also malignant tumours table 2. One case of malignant transformation has been described in the literature. May 29, 2014 educational video created by unmc college of dentistry class of 2016 dental students. It represents approximately 3 6% of all odontogenic tumors. It can occur at any age but most commonly in the second and third decades of life. Odontogenic myxoma of mandible appeared as an ameloblastoma. Odontogenic myxomas lack pdgfrb mutations reported in. Educational video created by unmc college of dentistry class of 2016 dental students. This paper reports a 6year followup case of an odontogenic myxoma treated with wide resection and mandibular bone reconstruction for posterior. Odontogenic myxoma is a benign odontogenic tumour that shows clinical and radiographic characteristics overlapping with other odontogenic lesions such as ameloblastoma and kcot. The predilection to involve the maxilla more than the mandible and the presence of welldeveloped internal osseous trabeculae differentiates myxoma from other odontogenic lesions. It is nonencapsulated, arises from odontogenic ectomesenchyme, develops solely in the jaws, and represent a small percentage of odontogenic tumor overall. Odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones.
Odontogenic myxoma segmental mandibulectomy stellate and spindleshaped cells immunohistochemical staining a b s t r a c t odontogenic myxoma om is a rare benign neoplasm with locally aggressive behavior. Jaw tumors and cysts symptoms and causes mayo clinic. Treatment, symptoms, causes, complications, diagnosis. Radiographically it presents most often as a multiloculated radiolucency 2. Untreated myxoma can be complicated by systemic embolization. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors 2. Odontogenic myxoma ddmfr oral and maxillofacial radiology. Right atrial myxoma images, diagnosis, treatment options. Deliverska, department of oral and maxillofacial surgery, faculty of dental medicine, medical university, sofia, bulgaria issn. Odontogenic myxoma definition of odontogenic myxoma by. Report of two cases sridhar p reddy 1, ananth naag 1, bina kashyap 2 1 department of oral and maxillofacial surgery, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india 2 department of oral pathology, st joseph dental college and hospital, duggirala, eluru, andhra pradesh, india. We present an unusual case of om as a rapidly expanding lesion in the mandible of a 62yearold woman who. Odontogenic myxoma om is a rare benign tumour originated from odontogenic ectomesenchyme,1 characterized by local invasion and tendency to reoccur. Odontogenic myxoma represents an uncommon benign neoplasm comprising of 36% of all odontogenic tumors.
An irregular soft tissue mass lesion is seen arising from right maxillary bone alveolar process, measuring 6 x 4. Ct and mri are highly accurate and greatly aid in diagnosis. A collection of disease information resources and questions answered by our genetic and rare diseases information specialists for odontogenic myxoma. To report the imaging characteristics of odontogenic myxoma om and compare the different imaging modalities used. When involving the maxilla, odontogenic myxomas can expand to inside the maxillary sinus, and are then diagnosed later only after having grown to larger sizes. The islands look identical to ameloblastoma, but that stroma is mature and dense whereas this ct is loose and resembles primitive dental papilla. We report a case of odontogenic myxoma in a 23 years old female who came with complaint of painless swelling in left mandible. Jan 30, 2019 myxoma as stated is a tumor present near the heart. Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors.
Computed tomography of odontogenic myxoma clinical radiology. In the majority of cases, diagnosis is largely dependent on the histopathological findings. Majority of myxomas that occur are present on the left side of the heart. These tumors are usually located on the atrial septum. The imaging characteristics of odontogenic myxoma and a. The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. This is a rare, slowgrowing, benign tumor that occurs most often in the lower jaw. Sudden death may occur in up to 15% patients with untreated atrial myxoma. There is no evidence in the literature in regard to the best treatment approach, in terms of conservative or aggressive surgery, for this type of tumor. Mar 19, 2012 the odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. Odontogenic myxoma is even rarer in children than in adults. As a myxoma, this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material. Fitted roc curves were constructed with data analysis software.
Odontogenic myxoma om is a benign intraosseous neoplasia, not very frequent, 1 but with high infiltrative potential that makes it a locally invasive tumor. The sunray or sunburst appearance in odontogenic myxoma has been reported in the literature although rarely. Benign odontogenic myxoid lesion composed of spindled to stellate cells. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a case managed. Conventional radiography, computed tomography ct, and magnetic resonance imaging mri with their inherent advantages and disadvantages should be routinely used in the diagnosis of odontogenic myxoma. A case of a rapidly expanding odontogenic myxoma of the mandible. The odontogenic myxoma is a rare, benign tumor that does not shed metastasis and involves the maxillomandibular complex. Diffusionweighted imaging in the evaluation of odontogenic. Published by publishing division, celesta software private limited. Diffusionweighted imaging in the evaluation of odontogenic cysts and tumours. The radiological appearance of this tumor is complicated and there exist controversies regarding its internal structure and locularity. To determine the imaging characteristics of softtissue myxoma, with emphasis on computed tomographic ct and magnetic resonance mr imaging findings and pathologic comparison. This tumour often presents as an asymptomatic expansile lesion without sensory nerve changes 2. Pdf the imaging characteristics of odontogenic myxoma and a.
This paper reports a case of odontogenic myxoma in a child treated with a. Mar 14, 2016 odontogenic myxoma is a benign odontogenic tumour of the jaw 1. Odontogenic myxoma is a rare, slowly growing, nonmetastasing tumour within the head and neck region. Axial ct section showing hypoattenuated image and, buccal and lingual. Most commonly it arises from mandible followed by maxilla. Pdf odontogenic myxoma is a relatively rare neoplasm which is almost exclusively seen in. Odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. Odontogenic myxoma om is a rare, nonencapsulated benign but locally invasive odontogenic tumor first described by thoma and goldman in 1947. Maxillary odontogenic myxoma involving the maxillary sinus.
There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Third most frequent odontogenic tumor after odontoma and ameloblastoma recurrence rate 25% odontogenic myxoma. Odontogenic myxoma of mandible appeared as an ameloblastoma on ct imaging pratiksha yadav 1 and dhaval thakkar 1 1department of radiodiagnosis, dr. Odontogenic fibroma and odontogenic myxoma are categorized as neoplasms composed of mesenchyme andor odontogenic ectomesenchyme with or without odontogenic epithelium in the world health organization 2005 classification of odontogenic tumours. Odontogenic myxoma of the maxilla a rare case report ramkumar subramaiam, 1 sangeetha narashiman, 2 malathi narasimhan, 3 veda giri, 4 and santhosh kumar 5 1 professor, department of oral and maxillofacial surgery, faculty of dental sciences, sri ramachandra university, ramachandra nagar, porur chennai, tamilnadu, india. Computed tomographic image showing involvement of the maxillary sinus with. Dr hemraj salodiya 1, dr shailesh bhuriya 1, dr lata kumari 1, dr.
It has sheets and strands of odontogenic epithelial cells. Odontogenic myxoma om is a benign but locally aggressive and nonmetastasising neoplasm of the jaws. Oct 22, 2009 surgery for sporadic atrial myxoma is usually curative. The purpose of our study was to identify the characteristic mr imaging features of intramuscular myxoma. Epidemiology typically seen in the 2nd to 3rd decades of life slightly earlier than ameloblastomas. Ijavst an open access journal issn 23203595 international journal of advanced veterinary science and technology 75 3 derakhshanfar, a. Odontogenic myxoma genetic and rare diseases information. Odontogenic myxomas in the hong kong chinese bir publications.
Benign odontogenic lesions are rare entities but are very important due to their locally aggressive nature. Odontogenic myxoma in the jaws is infrequent, accounting for only 3%6% of odontogenic tumours. As recent studies have reported pdgfrb recurrent driver mutations in myofibroma, we evaluated pdgfrb mutations in odontogenic myxomas. Comparison of the performance between frontier aspects software and. Imaging of softtissue myxoma with emphasis on ct and mr and. It is thought to arise from mesenchymal origin with cells of microscopic similarity to dental pulp and follicle 3. Odontogenic myxoma is a rare tumour of the jaw, making both its diagnosis and management challenging. Most cases diagnosed in 2nd 4th decades but wide age range of occurrence between 1 to 73 years. Odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Sunburst appearance in odontogenic myxoma of mandible. Odontogenic myxoma of the maxilla a rare case report.
Odontogenic myxoma is a rare benign tumor of ectomesenchymal origin, which can arise from dental papilla, follicle or periodontal ligament. Surgical management of an uncommon cutaneous myxoma in a dog. Patil medical college hospital and research centre, pimpri, pune, maharashtra, india. Odontogenic myxoma of the jaws is a rare benign tumor characterized grossly. Diagnostic value of mri for odontogenic tumours bir publications. Metron software, eponatech llc, creston, california. Odontogenic tumors at university of colorado health sciences.
The radiological images of 33 om cases were retrospectively analyzed. Conjunctival myxomas are thought to originate in tenons capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface squamous neoplasia ossn, or amelanotic melanoma. Odontogenic myxoma is a rare, benign intraosseous tumor. Odontogenic myxoma is a benign odontogenic tumour that shows clinical and.
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